Harnessing the Power of Theranostic Materials for Combining Therapy and Diagnostics
Investigation of the Sodium Molybdate - Zn2+ System of Mild Steel in Sea Water for Corrosion Inhibition Efficiency
Investigating the Effect of Autoclave Steam Sterilization on Anodized Implants for Color Fed Issue
Antiviral Nutraceuticals from Pomegranate (Punica granatum) Juice
Chemical Biology: What is its Role in Drug Discovery?
Microwave Assisted Vacuum Drying of Thompson Seedless Grapes: Analysis of Characteristics And Kinetic Modelling
Adsorption and Characterization of Anisaldehyde as Corrosion Inhibitor for Aluminium Corrosion in Hydrochloric Acidic Environment
Yeast Recovery in Batch Ethanol Fermentation
The Repercussion of Leachate from Industries on Water Quality in Jeedimetla Village and its Surroundings, Medchal-Malkajgiri District, Telangana
Studies on Solubility Enhancement of Telmisartan by Adsorption Method
A Review on Cardiovascular Disease Treatment using Nano Drug Technology
Investigating the Effect of Autoclave Steam Sterilization on Anodized Implants for Color Fed Issue
Production of Modified Carboxymethyl Cellulose from Sawdust and Wheat Straw
Yeast Recovery in Batch Ethanol Fermentation
Modeling of Chromium (VI) Adsorption on Limonia Acidissima Hull Powder Using Artificial Neural Network (ANN) Approach
In modern medicine, theranostics represents a revolutionary confluence of therapy and diagnostics, enabling customized treatment regimens catered to specific patient profiles. This study seeks to enable early disease identification and personalized treatment plans based on the unique subtype or genetic makeup of the ailment, with the goals of improving patient outcomes, decreasing unfavorable side effects, and increasing therapeutic efficacy. Theranostics improves therapy response rates by targeting specific patient traits to reduce resistance and recurrence rates. Furthermore, this paper allows the real-time tracking of therapeutic responses, enabling medical practitioners to modify therapies in response to patient responses. Theranostics has a significant impact on a number of medical specialties, including cancer, neurology, cardiology, and infectious illnesses, providing accurate and efficient treatment.
The examination of corrosion prevention effectiveness in various media demonstrates how the chemical properties of carbon steel can result in potent engineering uses. In this study, the corrosion inhibition efficiency of the Sodium Molybdate-Zn²+ system on carbon steel in seawater was evaluated using the weight loss method. The results of AC impedance investigations and surface analysis methods such as FTIR, AFM, and luminescence spectroscopy provide the basis of this study's mechanistic elements. Because zinc ions are believed to be efficient corrosion inhibitors for the protection offered by a cathodic polarization process, they have been used in this study. Together, Zn²+ and sodium molybdate stop carbon steel from corroding when it is submerged in seawater.
This study aimed to investigate the effect of steam sterilization treatments on anodized titanium devices (nails) of the same length and geometry. A fixed sterilization process was employed with the parameters: temperature of 121 °C, pressure of 15 psi, and autoclaving time of 30 minutes. The objective was to examine the color-fading issue after three autoclave cycles. During sterilization, two nail samples were wrapped in sterile cloth, while the other two samples were wrapped in aluminum foil. In each cycle, a total of four samples were used. Finally, all samples were visually analyzed for any signs of color fading. This study highlighted the adverse interaction between aluminum foil and steam, leading to potential moisture retention, chemical reactions, and surface damage. Conversely, sterile cloth allowed effective sterilization while preserving the anodized coating. These findings underscore the necessity of material-specific sterilization protocols to prevent damage to anodized implants, with sterile cloth recommended to maintain both sterilization efficacy and implant aesthetics. Further research into the long-term effects of high pressure and high- temperature sterilization on anodized surfaces is suggested.
Pomegranate (Punica granatum) boasts a rich history of medicinal use and is prized for its exceptional phytochemical composition. Abundant in bioactive compounds such as polyphenols, flavonoids, and tannins, pomegranate exhibits significant antiviral properties, acting through various mechanisms, including impeding viral attachment and entry, suppressing replication, and enhancing the immune response. This study has explored the antiviral efficacy of pomegranate juice extracts against a spectrum of viruses, including common pathogens. Findings suggest that the blend of blue and red colors in these extracts can inhibit viral replication and reduce viral load, making them promising candidates for antiviral therapeutics. Moreover, the high antioxidant content of these colors contributes to mitigating oxidative stress associated with viral infections. Furthermore, the immunomodulatory effects of the blue and red color blend enhance the body's natural defense against viruses by stimulating the release of cytokines and chemokines crucial for immune responses. This combination of antiviral and immune-boosting properties positions pomegranate juice as a promising natural antiviral agent. The safety and accessibility of pomegranate juice make it an attractive option for nutraceutical development, as it is widely consumed and easily incorporated into daily dietary practices. However, further research, including clinical trials, is needed to validate its efficacy and safety in the prevention and treatment of viral infections. Utilizing standardized pomegranate-based nutraceuticals or supplements presents a novel strategy for combating various viral ailments, offering a viable alternative to conventional antiviral therapies.
Chemical biology is a multidisciplinary subject that combines ideas from chemistry and biology to investigate the molecular mechanisms underlying physiological and pathological tactics. In drug discovery, chemical biology plays a pivotal function in elucidating the difficult interactions among small molecules and organic macromolecules, presenting essential insights that guide the improvement of novel healing agents. This study explores the fundamental contributions of chemical biology to drug discovery, emphasizing its impact on the right track identity, validation, and optimization. Chemical biology strategies allow the identification of capacity drug goals by way of probing the tricky community of molecular interactions within residing structures. Through the usage of chemical probes and revolutionary screening methods, this study selectively modulates unique organic pathways. Once identified, those targets undergo rigorous validation using chemical equipment that provides a precise and systematic assessment of their organic relevance. Moreover, chemical biology facilitates the optimization of lead compounds into drug applicants by offering precise information on shape-activity relationships and ability off-target results. This study includes the design and synthesis of small molecules that selectively engage with the goal, maximizing healing efficacy while minimizing adverse results. The combination of chemical biology strategies in drug discovery complements the efficiency of the drug development pipeline, accelerating the transition from goal identity to the hospital.
