Harnessing the Power of Theranostic Materials for Combining Therapy and Diagnostics
Chemical Biology: What is Its Role in Drug Discovery
Antiviral Nutraceuticals from Pomegranate (Punica granatum) Juice
STUDY ON INHIBITION EFFICIENCY OF TRISODIUM CITRATE- Zn2+ SYSTEM OF MILD STEEL IN SEA WATER LINKED WITH BIOLOGICAL SYSTEM
INVESTIGATING THE EFFECT OF AUTOCLAVE STEAM STERILIZATION ON ANODIZED COLOUR IMPLANTS FOR COLOR FED ISSUE
Microwave Assisted Vacuum Drying of Thompson Seedless Grapes: Analysis of Characteristics And Kinetic Modelling
Adsorption and Characterization of Anisaldehyde as Corrosion Inhibitor for Aluminium Corrosion in Hydrochloric Acidic Environment
Yeast Recovery in Batch Ethanol Fermentation
The Repercussion of Leachate from Industries on Water Quality in Jeedimetla Village and its Surroundings, Medchal-Malkajgiri District, Telangana
Studies on Solubility Enhancement of Telmisartan by Adsorption Method
A Review on Cardiovascular Disease Treatment using Nano Drug Technology
INVESTIGATING THE EFFECT OF AUTOCLAVE STEAM STERILIZATION ON ANODIZED COLOUR IMPLANTS FOR COLOR FED ISSUE
Production of Modified Carboxymethyl Cellulose from Sawdust and Wheat Straw
Yeast Recovery in Batch Ethanol Fermentation
Modeling of Chromium (VI) Adsorption on Limonia Acidissima Hull Powder Using Artificial Neural Network (ANN) Approach
In modern medicine, theranostics represents a revolutionary confluence of therapy and diagnostics, enabling customised treatment regimens catered to specific patient profiles. This novel technique seeks to enable early disease identification and personalised treatment plans based on the unique subtype or genetic makeup of the ailment, with the goals of improving patient outcomes, decreasing unfavourable side effects, and increasing therapeutic efficacy. Theranostics improves therapy response rates by targeting specific patient traits to reduce resistance and recurrence rates. Furthermore, this approach allows the real-time tracking of therapeutic responses, enabling medical practitioners to modify therapies in response to patient responses. Theranostics has a significant impact on a number of medical specialities, including cancer, neurology, cardiology, and infectious illnesses, providing accurate and efficient treatment.
Chemical biology is a multidisciplinary subject that combines ideas from chemistry and biology to investigate the molecular mechanisms underlying physiological and pathological tactics. inside the context of drug discovery, chemical biology plays a pivotal function in elucidating the difficult interactions among small molecules and organic macromolecules, presenting essential insights that guide the improvement of novel healing agents. This abstract explores the fundamental contributions of chemical biology to drug discovery, emphasizing its impact on the right track identity, validation, and optimization. Chemical biology strategies allow the identity of capacity drug goals by way of probing the tricky community of molecular interactions within residing structures. through the usage of chemical probes and revolutionary screening methods, researchers can selectively modulate unique organic pathways, uncovering potential healing goals for numerous diseases. once identified, those targets undergo rigorous validation using chemical equipment that provide a precise and systematic assessment of their organic relevance. moreover, chemical biology facilitates the optimization of lead compounds into drug applicants by using offering precise information on shape-activity relationships and ability off-target results. This procedure includes the design and synthesis of small molecules that selectively engage with the goal, maximizing healing efficacy while minimizing adverse results. the combination of chemical biology strategies in drug discovery complements the efficiency of the drug development pipeline, accelerating the transition from goal identity to the hospital.
Pomegranate (Punica granatum) boasts a rich history of medicinal use and is prized for its exceptional phytochemical composition. This abstract delves into the potential of utilizing a blend of blue and red colors in pomegranate juice as the foundation for antiviral nutraceuticals. Abundant in bioactive compounds such as polyphenols, flavonoids, and tannins, pomegranate exhibits significant antiviral properties, acting through various mechanisms, including impeding viral attachment and entry, suppressing replication, and enhancing the immune response. Research has explored the antiviral efficacy of pomegranate juice extracts against a spectrum of viruses, including common pathogens like mouth ulcer bacteria and the human immunodeficiency virus (HIV). Findings suggest that the blend of blue and red colors in these extracts can inhibit viral replication and reduce viral load, making them promising candidates for antiviral therapeutics. Moreover, the high antioxidant content of these colors contributes to mitigating oxidative stress associated with viral infections. Furthermore, the immunomodulatory effects of the blue and red color blend enhance the body's natural defense against viruses by stimulating the release of cytokines and chemokines crucial for immune responses. This combination of antiviral and immune-boosting properties positions pomegranate juice as a promising natural antiviral agent. The safety and accessibility of pomegranate juice make it an attractive option for nutraceutical development, as it is widely consumed and easily incorporated into daily dietary practices. However, further research, including clinical trials, is needed to validate its efficacy and safety in the prevention and treatment of viral infections. Utilizing standardized pomegranate-based nutraceuticals or supplements presents a novel strategy for combating various viral ailments, offering a viable alternative to conventional antiviral therapies. In conclusion, the blend of blue and red colors in pomegranate juice presents a compelling source of antiviral nutraceuticals, characterized by its allure, multifaceted mechanisms of action, and potential to significantly contribute to future antiviral strategies.
The investigation of corrosion prevention efficiency across a range of media shows us how carbon steel's chemical characteristics can lead to powerful engineering applications. The weight loss method was used in this work to assess the corrosion inhibition efficiencies of the TRISODIUM CITRATE - Zn2+ system on carbon steel in sea water. The mechanistic aspects of the work are based on the findings of AC impedance studies as well as surface examination techniques like FTIR, AFM, and luminescence spectroscopy. Zinc ions have been employed in this work because they are thought to be effective corrosion inhibitors for the defense provided by a cathodic polarization process. Zinc2+ and trisodium citrate work in concert to prevent corrosion in carbon steel submerged in seawater. Protective corrosion inhibitor surface coatings are incredibly effective at preventing cytotoxic and adverse allergic reactions, which can even result in acute or chronic body rejection, from occurring on a variety of medical metallic prosthesis. We have also discussed such bio-corrosion preventative strategies in our study.
The current laboratory study was to investigate the effect of steam sterilization treatments on anodized Titanium Nails of same length, operations and geometry using fixed sterilization process parameters (temperature 121°C, pressure 15 Psi and autoclaving time 30 minutes) for examine the colour fed issue after autoclave processing for 3 cycles. During sterilization the two Nail samples were used sterile cloth and other 2 samples used aluminium foil. All the samples were checked visually. Every cycle total four samples were used. Finally, all the samples were analysed visually.
