Pomegranate (Punica granatum) boasts a rich history of medicinal use and is prized for its exceptional phytochemical composition. This abstract delves into the potential of utilizing a blend of blue and red colors in pomegranate juice as the foundation for antiviral nutraceuticals. Abundant in bioactive compounds such as polyphenols, flavonoids, and tannins, pomegranate exhibits significant antiviral properties, acting through various mechanisms, including impeding viral attachment and entry, suppressing replication, and enhancing the immune response. Research has explored the antiviral efficacy of pomegranate juice extracts against a spectrum of viruses, including common pathogens like mouth ulcer bacteria and the human immunodeficiency virus (HIV). Findings suggest that the blend of blue and red colors in these extracts can inhibit viral replication and reduce viral load, making them promising candidates for antiviral therapeutics. Moreover, the high antioxidant content of these colors contributes to mitigating oxidative stress associated with viral infections. Furthermore, the immunomodulatory effects of the blue and red color blend enhance the body's natural defense against viruses by stimulating the release of cytokines and chemokines crucial for immune responses. This combination of antiviral and immune-boosting properties positions pomegranate juice as a promising natural antiviral agent. The safety and accessibility of pomegranate juice make it an attractive option for nutraceutical development, as it is widely consumed and easily incorporated into daily dietary practices. However, further research, including clinical trials, is needed to validate its efficacy and safety in the prevention and treatment of viral infections. Utilizing standardized pomegranate-based nutraceuticals or supplements presents a novel strategy for combating various viral ailments, offering a viable alternative to conventional antiviral therapies. In conclusion, the blend of blue and red colors in pomegranate juice presents a compelling source of antiviral nutraceuticals, characterized by its allure, multifaceted mechanisms of action, and potential to significantly contribute to future antiviral strategies.