i-manager Publications

i-manager's Journal on Material Science (JMS)

Current Issue Vol. 12 Issue 1

Most Cited

Electrical Properties of Nanocomposite Polymer Gels based on PMMA-DMA/DMC-LiCLO₂ -SiO₂
Comparison Of Composite Proton Conducting Polymer Gel Electrolytes Containing Weak Aromatic Acids
Enhancement in Electrical Properties of PEO Based Nano-Composite Gel Electrolytes
Effect of Donor Number of Plasticizers on Conductivity of Polymer Electrolytes Containing NH₄F
PMMA Based Polymer Gel Electrolyte Containing LiCF₃SO₃

Volume 11 Issue 4 January - March 2024

Research Paper

Reduced Graphene Oxide Synthesis by Hummer Method

Amandeep Kaur Rozi* , Harminder Singh, Deep Kamal Kaur Randhawa*, Anu Sheetal****

, Department of Electronics and Communication Engineering, Guru Nanak Dev University, Regional Campus, Jalandhar, Punjab, India.

Department of Mechanical Engineering, Guru Nanak Dev University, Amritsar, Punjab, India.

**** Department of Electronics and Communication Engineering, Guru Nanak Dev University, Regional Campus, Gurdaspur, Punjab, India.

Rozi, A. K., Singh, H., Randhawa, D. K. K., and Sheetal, A. (2024). Reduced Graphene Oxide Synthesis by Hummer Method. i-manager’s Journal on Material Science, 11(4), 1-7. https://doi.org/10.26634/jms.11.4.20557

Abstract

In this study, Graphite Oxide (GO) film with a 2-D structure was successfully synthesized via the Hummer method. The GO film was further reduced by hydrazine to form a few layers of graphene. The graphite oxide and reduced graphene oxide synthesized in this study were characterized by Scanning Electron Microscopy (SEM), Raman spectroscopy, and XRD analysis. A low-cost method using simple chemicals was employed to synthesize GO films with high conductivity on a large scale. The synthesized reduced graphene oxide can serve as an excellent material for various applications due to its lower cost and higher thermal, mechanical, and electrical conductivity. Large surface area graphene-based sensors and solar cells can efficiently replace expensive Carbon Nanotubes (CNTs).

References

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Research Paper

Enhanced Urease-Driven Nanobots for Radionuclide-Based Bladder Cancer Therapy

S. Mohammed Sahil* , S. Atheena Milagi Pandian, Rashika Murugan*

*-*** Atheenapandian Private Limited, India.

Sahil, S. M., Pandian, S. A. M., and Murugan, R. (2024). Enhanced Urease-Driven Nanobots for Radionuclide-Based Bladder Cancer Therapy. i-manager’s Journal on Material Science, 11(4), 8-14. https://doi.org/10.26634/jms.11.4.20821

Abstract

Bladder cancer treatment with intravenous medication delivery has reasonable survival rates but modest therapeutic efficacy. Taking advantage of their superior diffusion and mixing capacities in urine compared to traditional pharmaceuticals or passive nanoparticles, self-propelled nanoparticles, also known as nanobots, have been proposed as a solution to the latter issue. Nonetheless, nothing is known about how well nanobots can translate into bladder cancer treatments. Here, urease-powered, radiolabelled mesoporous silica-based nanobots were evaluated in an orthotopic animal model of bladder cancer. Both in vivo and ex vivo findings showed increased accumulation of nanobots at the tumor location; positron emission tomography in vivo showed an eight-fold increase. The ex vivo tumor penetration by nanobots was validated by label-free optical contrast based on polarization-dependent scattered light-sheet microscopy of cleared bladders. Intravesically treatment was given to tumor-bearing mice. About 90% less tumor size was observed when radio-iodinated nanobots were used for radionuclide therapy, establishing nanobots as effective delivery nanosystems for bladder cancer treatment.

References

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[2]. Akolpoglu, M. B., Alapan, Y., Dogan, N. O., Baltaci, S. F., Yasa, O., Aybar Tural, G., & Sitti, M. (2022). Magnetically steerable bacterial microrobots moving in 3D biological matrices for stimuli-responsive cargo delivery. Science Advances, 8(28), eabo6163.

[3]. Arqué, X., Patiño, T., & Sánchez, S. (2022). Enzyme- powered micro-and nano-motors: Key parameters for an application-oriented design. Chemical Science, 13(32), 9128-9146.

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[12]. Sun, Z., Wang, T., Wang, J., Xu, J., Shen, T., Zhang, T., ... & Hou, Y. (2023). Self-propelled Janus nanocatalytic robots guided by magnetic resonance imaging for enhanced tumor penetration and therapy. Journal of the American Chemical Society, 145(20), 11019-11032.

[13]. Urso, L., Nieri, A., Uccelli, L., Castello, A., Artioli, P., Cittanti, C., ... & Bartolomei, M. (2023). Lutathera® orphans: State of the art and future application of radioligand therapy with 177Lu-DOTATATE. Pharmaceutics, 15(4), 1110.

[14]. Venugopalan, P. L., Esteban-Fernandez de Avila, B., Pal, M., Ghosh, A., & Wang, J. (2020). Fantastic voyage of nanomotors into the cell. American Chemical Society (ACS), 14(8), 9423-9439.

[15]. Wan, M., Wang, Q., Li, X., Xu, B., Fang, D., Li, T., ... & Wei, J. (2020). Systematic research and evaluation models of nanomotors for cancer combined therapy. Angewandte Chemie International Edition, 59(34), 14458-14465.

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Review Paper

Exploring the Role of Biomaterials in Organ Implants

Atheena Milagi Pandian S.* , Rashika Murugan, N. Sri Manoj Kumar, M. Sudherson, M. Kriya Sakthi

*-***** Atheenapandian Private Limited, Tamil Nadu, India.

Pandian, S. A. M., Murugan, R., Kumar, N. S. M., Sudherson, M., and Sakthi, M. K. (2024). Exploring the Role of Biomaterials in Organ Implants. i-manager’s Journal on Material Science, 11(4), 15-25. https://doi.org/10.26634/jms.11.4.20622

Abstract

There are several classifications that describe the way materials function in the body. Devices that mimic a portion or function of the body in a safe, dependable, cost-effective, and physiologically appropriate way are made using biomaterials. Numerous tools and substances are now employed in the treatment of illness or injury, including everyday objects like tooth fillings, sutures, needles, catheters, plates, and so on. As time goes on, a synthetic substance that functions in close contact with live tissue or replaces a portion of a biological system might be summed up as a biomaterial. A biomaterial is described as "a systemically and pharmacologically inert substance designed for implantation within or incorporation with living things" by the Clemson University Advisory Board for Biomaterials. Materials, whether synthetic or natural, that may be utilized in any system that treats, enhances, or substitutes any organ, tissue, or bodily function for any length of time or on the other hand, a biological substance is one that is created by a biological system, like skin or an artery.

References

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[9]. Sezer, N., Evis, Z., Kayhan, S. M., Tahmasebifar, A., & Koç, M. (2018). Review of magnesium-based biomaterials and their applications. Journal of Magnesium and Alloys, 6(1), 23-43.

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Review Paper

Progress in Materials for 3D Printing

Rashika Murugan* , S. Atheena Milagi Pandian, M. Sudherson*, N. Sri Manoj Kumar****

*-**** Atheenapandian Private Limited, Tamil Nadu, India.

Murugan, R., Pandian, S. A. M., Sudherson, M., and Kumar, N. S. M. (2024). Progress in Materials for 3D Printing. i-manager’s Journal on Material Science, 11(4), 26-35. https://doi.org/10.26634/jms.11.4.20530

Abstract

The realm of 3D printing is rapidly evolving, offering a wide range of options from typical thermoplastics to advanced graphene-based composites. This technology improves production efficiency and gives consumers more control over customizing products and specifications. However, alongside its transformative potential, 3D printing also presents challenges, such as potential impacts on manufacturing jobs and security issues. Since its modest beginnings in developing visualization models, 3D printing has evolved to transform the manufacturing of distinct devices, implants, tissue engineering scaffolds, and drug delivery systems. This paper explores the most recent progress in 3D printing materials, including smart materials, ceramics, electronics, biomaterials, and composites, emphasizing the significance of adapting to changing materials and product requirements. It delves into the complex connection between printing parameters and the characteristics of printed composite parts, providing new opportunities to improve the strength and functionality of 3D-printed components. This review highlights how 3D printing can be utilized in various industries, such as medical devices and explosives research, using materials such as titanium, aluminum, carbon fiber, and thermoplastic polyurethanes. With the continuous growth of the 3D printing field, it is essential to adopt new methods and materials to fully realize its impact on the future of manufacturing and product development.

References

[1]. Amza, C. G., Zapciu, A., Constantin, G., Baciu, F., & Vasile, M. I. (2021). Enhancing mechanical properties of polymer 3D printed parts. Polymers, 13(4), 562.

[2]. Bai, D. Y., Yao, Y. D., Liu, J. P., Xu, S., Kang, L. M., Liu, D. B., ... & Li, Y. (2023, June). Study on the safety of modified aluminum powder in 3D printing process. In Journal of Physics: Conference Series, 2478 (3), 032081. IOP Publishing.

[3]. Chen, Z., Zhao, D., Liu, B., Nian, G., Li, X., Yin, J., ... & Yang, W. (2019). 3D printing of multifunctional hydrogels. Advanced Functional Materials, 29(20), 1900971.

[4]. Fenollosa-Artes, F., Jorand, L., Tejo-Otero, A., Lustig-Gainza, P., Romero-Sabat, G., Medel, S., & Uceda, R. (2023). Soft 3D printing of thermoplastic polyurethane: Preliminary study. In Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture, 237(6-7), 1128-1135.

[5]. Fu, K., Yao, Y., Dai, J., & Hu, L. (2017). Progress in 3D printing of carbon materials for energy related applications. Advanced Materials, 29(9), 1603486.

[6]. Gopinathan, J., & Noh, I. (2018). Recent trends in bioinks for 3D printing. Biomaterials Research, 22(1), 11.

[7]. Guessasma, S., Belhabib, S., & Nouri, H. (2019). Printability and tensile performance of 3D printed polyethylene terephthalate glycol using fused deposition modelling. Polymers, 11(7), 1220.

[8]. Haghdadi, N., Laleh, M., Moyle, M., & Primig, S. (2021). Additive manufacturing of steels: A review of achievements and challenges. Journal of Materials Science, 56, 64-107.

[9]. Hajare, D. M., & Gajbhiye, T. S. (2022). Additive manufacturing (3D printing): Recent progress on advancement of materials and challenges. Materials Today: Proceedings, 58, 736-743.

[10]. He, Y., Yang, F., Zhao, H., Gao, Q., Xia, B., & Fu, J. (2016). Research on the printability of hydrogels in 3D bioprinting. Scientific Reports, 6(1), 29977.

[11]. Hu, Q., Duan, Y., Zhang, H., Liu, D., Yan, B., & Peng, F. (2018). Manufacturing and 3D printing of continuous carbon fiber prepreg filament. Journal of Materials Science, 53, 1887-1898.

[12]. Khosravani, M. R., Schüürmann, J., Berto, F., & Reinicke, T. (2021). On the post-processing of 3D-printed ABS parts. Polymers, 13(10), 1559.

[13]. Liu, X., Yuk, H., Lin, S., Parada, G. A., Tang, T. C., Tham, E., ... & Zhao, X. (2018). 3D printing of living responsive materials and devices. Advanced Materials, 30(4), 1704821.

[14]. Mann, V., Krokhin, A., Alabin, A., Zmanovskiy, S., Konkevich, V., & Redkin, I. (2017). Evolution of aluminum alloys structure at production phases of 3D products by methods of additive technologies. In TMS 2017 146th Annual Meeting & Exhibition Supplemental Proceedings (pp. 49-59). Springer International Publishing.

[15]. Ong, C. S., Yesantharao, P., Huang, C. Y., Mattson, G., Boktor, J., Fukunishi, T., ... & Hibino, N. (2018). 3D bioprinting using stem cells. Pediatric Research, 83(1), 223-231.

[16]. Raj, S. A., Muthukumaran, E., & Jayakrishna, K. (2018). A case study of 3D printed PLA and its mechanical properties. Materials Today: Proceedings, 5(5), 11219-11226.

[17]. Sidambe, A. T. (2014). Biocompatibility of advanced manufactured titanium implants—A review. Materials, 7(12), 8168-8188.

[18]. Tümer, E. H., & Erbil, H. Y. (2021). Extrusion-based 3D printing applications of PLA composites: A review. Coatings, 11(4), 390.

[19]. Xiao, J., & Gao, Y. (2017). The manufacture of 3D printing of medical grade TPU. Progress in Additive Manufacturing, 2, 117-123.

[20]. Yu, L., Chen, K., Xue, P., Cui, Y., & Jia, M. (2021). Impregnation modeling and preparation optimization of continuous glass fiber reinforced polylactic acid filament for 3D printing. Polymer Composites, 42(11), 5731-5742.

[21]. Zhao, Z., Tian, X., & Song, X. (2020). Engineering materials with light: Recent progress in digital light processing based 3D printing. Journal of Materials Chemistry C, 8(40), 13896-13917.

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Review Paper

The Significance of Bioprinting Methods in Bioprinting for Tissue Engineering

Atheena Milagi Pandian S.* , Rashika Murugan, N. Sri Manoj Kumar*, S. Mohammed Sahil****

*-**** Atheenapandian Private Limited, Tamil Nadu, India.

Pandian, S. A. M., Murugan, R., Kumar, N. S. M., and Sahil, S. M. (2024). The Significance of Bioprinting Methods in Bioprinting for Tissue Engineering. i-manager’s Journal on Material Science, 11(4), 36-43. https://doi.org/10.26634/jms.11.4.20529

Abstract

Bioprinting has been a trending technology in recent years. It is a combination of engineering and biology. It can be used in the fields of tissue engineering and drug screening. It can be used to print 3D structures using 3D modeling software and to print with cultured cells. Bioink should have cells with the following characteristics: cell viability, cell differentiation, degradation, biocompatibility, and printability. Bioink contains biomaterials, living cells, and growth factors that are used to grow the cells. The replaced cells should possess chemical, physical, and mechanical properties. There are several methods to print biological organs, including microextrusion, inkjet bioprinting, and stereolithography.

References

[1]. Derakhshanfar, S., Mbeleck, R., Xu, K., Zhang, X., Zhong, W., & Xing, M. (2018). 3D bioprinting for biomedical devices and tissue engineering: A review of recent trends and advances. Bioactive Materials, 3(2), 144-156.

[2]. Huang, Y., Zhang, X. F., Gao, G., Yonezawa, T., & Cui, X. (2017). 3D bioprinting and the current applications in tissue engineering. Biotechnology Journal, 12(8), 1600734.

[3]. Hussein, A., Hao, L., Yan, C., Everson, R., & Young, P. (2013). Advanced lattice support structures for metal additive manufacturing. Journal of Materials Processing Technology, 213(7), 1019-1026.

[4]. Kačarević, Ž. P., Rider, P. M., Alkildani, S., Retnasingh, S., Smeets, R., Jung, O., ... & Barbeck, M. (2018). An introduction to 3D bioprinting: Possibilities, challenges and future aspects. Materials, 11(11), 2199.

[5]. Khorsandi, D., Fahimipour, A., Saber, S. S., Ahmad, A., & De Stephanis, A. A. (2019). Fused deposition modeling and stereolithography 3D bioprinting in dental science. EC Dental Science, 18(2019), 110-115.

[6]. Kumar, H., & Kim, K. (2020). Stereolithography 3D bioprinting. 3D Bioprinting: Principles and Protocols (pp. 93-108).

[7]. Masood, S. H., Mau, K., & Song, W. Q. (2010, October). Tensile properties of processed FDM polycarbonate material. In Materials Science Forum, 654, 2556-2559.

[8]. Murphy, S. V., & Atala, A. (2014). 3D bioprinting of tissues and organs. Nature Biotechnology, 32(8), 773-785.

[9]. Ozbolat, I., & Gudapati, H. (2016). A review on design for bioprinting. Bioprinting, 3, 1-14.

[10]. Pereira, R. F., & Bártolo, P. J. (2015). 3D bioprinting of photocrosslinkable hydrogel constructs. Journal of Applied Polymer Science, 132(48).

[11]. Safronov, V. A., Khmyrov, R. S., Kotoban, D. V., & Gusarov, A. V. (2017). Distortions and residual stresses at layer-by-layer additive manufacturing by fusion. Journal of Manufacturing Science and Engineering, 139(3), 031017.

[12]. Swetham, T., Reddy, K. M. M., Huggi, A., & Kumar, M. N. (2017). A critical review on of 3D printing materials and details of materials used in FDM. International Journal of Scientific Research in Science, Engineering and Technology (IJSRSET), 3, 353-361.

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i-manager's Journal on Material Science (JMS)

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Volume 11 Issue 4 January - March 2024

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Rozi, A. K., Singh, H., Randhawa, D. K. K., and Sheetal, A. (2024). Reduced Graphene Oxide Synthesis by Hummer Method. i-manager’s Journal on Material Science, 11(4), 1-7. https://doi.org/10.26634/jms.11.4.20557

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Enhanced Urease-Driven Nanobots for Radionuclide-Based Bladder Cancer Therapy

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Exploring the Role of Biomaterials in Organ Implants

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Progress in Materials for 3D Printing

Rashika Murugan* , S. Atheena Milagi Pandian**, M. Sudherson***, N. Sri Manoj Kumar****

*-**** Atheenapandian Private Limited, Tamil Nadu, India.

Murugan, R., Pandian, S. A. M., Sudherson, M., and Kumar, N. S. M. (2024). Progress in Materials for 3D Printing. i-manager’s Journal on Material Science, 11(4), 26-35. https://doi.org/10.26634/jms.11.4.20530

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The Significance of Bioprinting Methods in Bioprinting for Tissue Engineering

Atheena Milagi Pandian S.* , Rashika Murugan**, N. Sri Manoj Kumar***, S. Mohammed Sahil****

*-**** Atheenapandian Private Limited, Tamil Nadu, India.

Pandian, S. A. M., Murugan, R., Kumar, N. S. M., and Sahil, S. M. (2024). The Significance of Bioprinting Methods in Bioprinting for Tissue Engineering. i-manager’s Journal on Material Science, 11(4), 36-43. https://doi.org/10.26634/jms.11.4.20529

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Amandeep Kaur Rozi* , Harminder Singh, Deep Kamal Kaur Randhawa*, Anu Sheetal****

S. Mohammed Sahil* , S. Atheena Milagi Pandian, Rashika Murugan*

Atheena Milagi Pandian S.* , Rashika Murugan, N. Sri Manoj Kumar, M. Sudherson, M. Kriya Sakthi

Rashika Murugan* , S. Atheena Milagi Pandian, M. Sudherson*, N. Sri Manoj Kumar****

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