Prodrug Design for Enhancing Drug Efficacy and Safety
An Overview of the Medicinal Significance of Boerhaavia diffusa
A Review on Ethnopharmacological Study of Clitoria ternatea
A Review Study on Medicinal Significance of Convolvulus pluricaulis
An Systemic Overview of Pharmacognostical and Therapeutical Herbal Application of Gymnema sylvestre
Yeast Recovery in Batch Ethanol Fermentation
The Repercussion of Leachate from Industries on Water Quality in Jeedimetla Village and its Surroundings, Medchal-Malkajgiri District, Telangana
Microwave Assisted Vacuum Drying of Thompson Seedless Grapes: Analysis of Characteristics And Kinetic Modelling
Studies on Solubility Enhancement of Telmisartan by Adsorption Method
Adsorption and Characterization of Anisaldehyde as Corrosion Inhibitor for Aluminium Corrosion in Hydrochloric Acidic Environment
Prodrug Design for Enhancing Drug Efficacy and Safety
Synthesis of a Moringa Based Coagulant Functionalized by Iron Oxide Nanoparticles
Production of Modified Carboxymethyl Cellulose from Sawdust and Wheat Straw
Yeast Recovery in Batch Ethanol Fermentation
Modeling of Chromium (VI) Adsorption on Limonia Acidissima Hull Powder Using Artificial Neural Network (ANN) Approach
Interfaces, where different fluids meet, are crucial zones influencing processes like emulsification and foam creation. Understanding their properties is vital in chemical, biosciences and oil industry. Rheology, evaluating stress and strain, helps characterize these properties, distinguishing between material behavior like elasticity and viscosity. Stress causes deformation, crucial in defining a material's response. Elastic materials return to shape after stress, maintaining ratios. Interfacial studies benefit diverse fields like engineering, biology, and medicine, unveiling unique properties for material design. In biology, studying bio-interfaces elucidates complex cell behaviors and drug delivery. Recent research emphasizes the importance of studying interfaces. Peptide interfaces exhibit self-organization in cell elongation, while motor protein-based nano-biodevices and antimicrobial implant surfaces demonstrate new applications. Interfacial studies impact nanocomposites, dental materials, cancer stem cells, and nanospheres, showcasing their broad implications in diverse fields. Nanotechnology combined with biology creates new medical possibilities. Nanomedicine, using nanoparticles, shows promise in drug delivery and cancer treatment. Challenges exist in understanding bio-interfaces, crucial for medical progress. Advances in nanotech and interfacial studies could transform fields with ongoing research needed for big changes.
Melia dubia, also referred to as Malabar neem, is a potential multipurpose tree ideal for agroforestry to increase yield per unit of land. It has several medical, pharmacological, ethnomedicinal, and conventional qualities and uses, including antioxidant, anticancer, antibacterial, and antidiabetic actions, and is widely sought after in herbal medicine. The aim of this paper is to assess the biological characteristics of Melia dubia seeds through phytochemical characterization. The study emphasizes preliminary phytochemical analysis, total alkaloid content, in vitro antioxidant activity, and antimicrobial activities. The ferric-reducing antioxidant power method and nitric oxide radical scavenging activity methods were employed to examine the extract's antioxidant activity. For determining its antimicrobial activity, disc diffusion was used. It can be concluded that the ethanolic extract of Melia dubia seeds contains alkaloids, and the seeds exhibit both antimicrobial and antioxidant properties.
Functional dyes play a pivotal role in various industries, spanning from textiles to electronics, due to their unique properties and diverse applications. This review provides a comprehensive overview of the design, development, and cutting-edge applications of functional dyes. The exploration begins with an examination of the fundamental principles governing dye design, including molecular structure, color chemistry, and synthesis techniques. Subsequently, the focus shifts towards the development of novel functional dyes, encompassing advances in organic, inorganic, and hybrid dye materials. Emphasis is placed on the exploration of sustainable and environmentally friendly dye synthesis methods, aiming to minimize ecological impact while maintaining optimal performance. The review further delves into the diverse applications of functional dyes in high-tech industries. It explores their utilization in Organic Light-Emitting Diodes (OLEDs), photovoltaic devices, biomedical imaging, and sensing technologies. Additionally, their incorporation in smart textiles, wearable electronics, and display technologies is highlighted, elucidating their role in fostering innovation and technological advancement. Moreover, this review underscores the challenges and prospects associated with functional dye research and applications. It discusses the hurdles in achieving commercial scalability, durability, and stability of functional dyes, while also presenting potential avenues for future research and development. In summary, this review consolidates the current state of knowledge in the field of functional dyes, offering valuable insights for researchers, technologists, and industries aiming to harness the potential of these versatile materials in various high-tech applications.
This study defines effectual methodologies to measure the antioxidant activity of Sorghum. Some different types of phenol with fluctuating properties exist, but their relatively diminutive exertion to establish the potential of these compounds in human health has been reported. Antioxidants are used for the reserve process of oxidation. These are primarily used in food preservation and in the petroleum industry to protect them from corrosion. Of all the cereals, sorghum has the capability to be bred specifically to produce high levels of different phenol that can be easily concentrated by simple processes. This special sorghum has reasonable grain yields and agronomic traits that make them productive and economical. Different methods are being used to determine these compounds, such as the DPPH method, ABTS, and ORAC technique. The prospect is good, but significant investment is required to make obvious feeding trials and their health-endorsing characteristics.
Computational software tools are now routinely used to investigate the structure, dynamics, surface properties, and thermodynamics of inorganic, biological, and polymeric systems. These tools are a vital part of the guide for drug discovery and are widely used in rational drug design and structure-based drug design processes. The process of drug design and discovery is essential in the invention of a new chemical entity. For this process, plenty of computational tools are available globally. These computational software tools are fast, free, open online access, and paid. Pharmaceutical software decreases human efforts, errors, and time utilization in a particular task without compromising the quality of work, with great accuracy and efficiency. This software is utilized by various institutes globally related to science and medicine. A computer application applies a library of medicinal chemical transformation rules to an input structure and then permits evaluation of the resulting output structures. Computer-Aided Drug Design (CADD) is now widely recognized as a viable alternative and complements high throughput screening. The search for new molecular entities has led to the construction of high-quality datasets and design libraries that may be optimized for molecular diversity or similarity. Conversely, advances in molecular docking algorithms, combined with improvements in computational infrastructure, are enabling rapid improvement in screening throughput.