This paper describes the design and simulation of a Planar Inverted-F Antenna (PIFA) covering multiple bands by HFSS simulator. Simple structure and easy to manufacture is the key of the proposed antenna. It fulfills wireless communication application and also it is compact and efficient. The proposed antenna covers bands DCS (1710-1800 MHz), GSM (880- 960 MHz), PCS (1850-1990 MHZ), Bluetooth (2400 MHz), UMTS (1920-2170 MHz), WiBro (2300-2390 MHz), WCS band (2305-2320 MHz), LTE 2300 (2300-2400 MHz), LTE 2500 (2600-2690 GHz) and Wimax (2.3 GHz). A directional radiation pattern is observed within the mentioned bandwidth. S11 plot and various parametric analysis has been done for an improved response. The objective of this paper is to design a compact antenna, which could be used for different wireless applications such as mobile and should be compatible with the present demand, i.e. 3G and 4G.