The present work has been carried out to characterize the dynamics of three-phase flow in cylindrical bubble column, run under homogeneous bubble flow and heterogeneous flow conditions using CFD simulation. Investigation has been done to study the effect of process variables such as, inlet gas velocity, solid loading, and particle size on flow pattern in three-phase bubble column. The simulations were performed for air-water-glass beads in a bubble column of 0.6 m height, 0.1 m i.d. and 0.05 m sparger diameter to study the flow pattern. Eulerian-Eulerian three-phase simulations with k-e turbulence for liquid phase were carried out using commercial flow CFD software CFX-5.6, with a focus on characterizing the dynamics properties of gas liquid solid flows. Good agreement was obtained between available experimental data and simulation. The flow pattern profiles obtained for various parametric studies appear to be sensible and logical. The results presented are useful for understanding the dynamics of gas-liquid-solid flows in bubble column and provides a basis for further development of CFD model for three phase systems.