The narrative in this discourse provides the third part of an epistemological rational for the novel discipline of “Trioinformatics”. This novel application of trioinformatic notation in mathematical form is the continuation of the Trioinformatics article that appeared in the March–May i-manager’s Journal on Circuits and Systems,“Trichotomous Charge States” [denoted by the acronym “TCS”] use “Neuroengineering Neuromathematics Notation” as the explicative expression of Trioinformatics in “Polyphase Electrical Systems” and electronic “Tri–State Buffers”. Trioinformatics Neuroengineering also has broad applications when used as an innovative way of explaining the transition from trichotomous logic (Osler, 2015) into trichotomous Triple–I (Osler, 2013d) research questions and associated instrumentation [first introduced in the i-manager’s Journal on Mathematics as a part of the Tri–Squared Test (Osler, 2012a)]. Trioinformatics is an in–depth way of symbolically illustrating the law of trichotomy and a mathematically–grounded rational technique for explaining the ternary properties of electronic circuitry (Osler, 2015). The use of Trioinformatics also adds value to investigative inquiry through the efficacy of digital instruments and tools via eduscientifically–engineered (Osler, 2013) research designs (Osler, 2015). Additional research into trioinformatics and its neuroengineered neuromathematical notation will further advance in–depth investigations into the tripartite aspects of digital instrumentation and digital / electronic circuitry.