Base isolation technique is one of the most widely implemented seismic protection systems in earthquake prone areas. The term 'base' refers to the foundation of a structure and 'isolation' refers to reduced interaction between the ground and the structure resting over it. Base isolation is a very effective way to counteract the damaging component of seismic forces and is one of the most widely implemented and accepted seismic protection systems. The mechanism of the base isolator increases the natural period of the overall structure, and decreases its acceleration response to earthquake / seismic motion.A multi-storied R.C.C (Reinforced Cement Concrete) building with lead rubber bearing is introduced throughout this study.Validation of SAP2000 for base isolation technique using a mathematical model is carried out. Comparison between base shear values considering fixed base for the static and dynamic analysis is shown. Also the comparison between the base shear values of fixed and isolated base considering dynamic analysis (response spectrum and linear time history) is explored. For response spectrum analysis, the reduction in base shear value for base isolated building is upto 62%, whereas for the same base isolated building and for linear time history analysis, this reduction is upto 85% - 90%.