An earthquake is a sudden violent shaking of the ground. Many aseismic construction designs and technologies have been developed over the years in attempts to mitigate the effects of earthquakes on buildings, bridges and potentially vulnerable contents. Seismic Isolation is a relatively recent, and evolving, technology of this kind. Though the concept of base isolation as a means of earthquake protection is more than 100-years old, its application to civil engineering structures is relatively new, and the base isolation research is pursued in India only for the last twenty years. This paper introduces the concept of Natural rubber base-isolators for the seismic (earthquake) resistance of Reinforced Concrete (RC) – framed buildings. The design of base isolators is explained with an objective to bring awareness and confidence in structural engineers in India for use of this technique in seismic areas. In addition, an analytical study is carried out to validate the effectiveness of base isolators in RC structures using SAP2000 NL.