The place of work can sometimes be hazardous to health, even fatal occupational hazards is one of the most important health problems in the world, especially in developing countries. Fishing is a well-known industry and there are certain risks of work-related diseases and accidents, occupational hazards and safety issues. In response to this issue, interventions such as video-assisted teaching programs are being developed to enhance fishers' knowledge and attitudes toward occupational hazards. Video Assisted Teaching will improve the knowledge and attitude regarding occupational hazards and its prevention. The research design chosen for this study was quasi-experimental non- randomized control group design. Purposive sampling technique was used. The sample size comprised of 60 fishers out of which 30 was in the experimental group and 30 was in the control group. Demographic data, occupational data and Structured Knowledge Questionnaire for pre-test and post-test were administered in face to face method, after getting informed consent. Video assisted teaching programme regarding occupational hazards and its prevention was administered to the experimental group. The data were analyzed based on objective and hypotheses of the study The Video Assisted Teaching Programme was effective in increasing the knowledge score and change attitude. There was significant positive relationship between post-test knowledge score and post-test attitude score regarding occupational hazards and its prevention among fishers. There was significant association between pre-test level of knowledge and educational status, source of information and place of fishing. There was significant association between pre-test level of attitude and educational status, source of information and place of fishing. The study concluded that Video Assisted Teaching Programme is an effective intervention in increasing knowledge and changing attitude among fishers.