Prosthodontic care for individuals with neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease requires a tailored approach because of the unique challenges these patients face. A study by the Institute for Health Metrics and Evaluation (IHME) reported that neurological conditions, including neurodegenerative diseases, affected 43.1% of the global population in 2021. This review provides an updated overview of modified treatment planning strategies for patients with common neurodegenerative disorders. Clinical literature demonstrates how these conditions affect oral health and outlines the prosthodontic approaches used in their management. The review also stresses the important role of prosthodontics in managing patients with neurological impairments. Neurodegeneration is a key pathophysiological factor in most brain-related disorders.