Electromagnetic interference (EMI) generated by DC/DC power converters presents a significant challenge, particularly within the 9–150 kHz frequency range. This paper introduces novel pseudo-random modulation (RanM) techniques designed to shape the EMI spectrum without compromising energy efficiency or power density. Implemented using a cyber-physical system (CPS) with a National Instruments PXI and FPGA platform, these techniques demonstrate effective EMI mitigation. The approach provides a 30% reduction in Frame Error Rate (FER) in Power Line Communication (PLC) systems and conforms with standard EMI compliance requirements. Comprehensive hardware implementation and validation confirm the effectiveness and practical feasibility of the proposed techniques.