This study aimed to investigate the effect of steam sterilization treatments on anodized titanium devices (nails) of the same length and geometry. A fixed sterilization process was employed with the parameters: temperature of 121 °C, pressure of 15 psi, and autoclaving time of 30 minutes. The objective was to examine the color-fading issue after three autoclave cycles. During sterilization, two nail samples were wrapped in sterile cloth, while the other two samples were wrapped in aluminum foil. In each cycle, a total of four samples were used. Finally, all samples were visually analyzed for any signs of color fading. This study highlighted the adverse interaction between aluminum foil and steam, leading to potential moisture retention, chemical reactions, and surface damage. Conversely, sterile cloth allowed effective sterilization while preserving the anodized coating. These findings underscore the necessity of material-specific sterilization protocols to prevent damage to anodized implants, with sterile cloth recommended to maintain both sterilization efficacy and implant aesthetics. Further research into the long-term effects of high pressure and high- temperature sterilization on anodized surfaces is suggested.