This study investigated human resources management and teachers' efficiency in public secondary schools in Bayelsa State. A correlational design was adopted for this purpose. A sample of 100 administrative staff was drawn from the population of staff at the Bayelsa State Post Primary School Board using a simple random sampling technique. A 16-item questionnaire titled "Human Resources Management and Teachers' Efficiency Questionnaire (HRMTEQ)" was developed on a 4-point scale for data collection. The reliability of the instrument was determined using the Pearson productmoment correlation coefficient, which yielded a reliability coefficient of 0.86. Data collected were analyzed using the mean. Findings from the study indicate that human resource management practices significantly influence teachers' efficiency. The study recommends that post primary school boards should organize training programs for teachers, award certificates of recognition to deserving school heads and teachers, and implement disciplinary measures for erring teachers to prevent unexpected behavior.