The objective of this study was to evaluate the effectiveness of constraint-induced movement therapy on motor function among stroke patients in selected hospitals in Erode, Tamil Nadu, India. A quasi-experimental design with a pre-test and post-test control group was used. The study was based on a modified version of Wiedenbach's Helping Art of Clinical Nursing Theory. A purposive sampling technique selected 60 participants, 30 in the experimental group and 30 in the control group. A pre-test was conducted using the Fugl-Meyer Assessment Scale. In the experimental group, the researcher demonstrated and assisted participants with range-of-motion exercises for 30 minutes, and activities of daily living were performed. Data were analyzed using descriptive and inferential statistics. Regarding motor function, the mean post-test score in the experimental group was 77.13 (SD ± 9.85), compared to 45.3 (SD ± 8.53) in the control group. The independent t-value was 12.83, significant at p < 0.05. No significant association was found between posttest scores and demographic variables, except for family monthly income (χ2 = 12.59, p < 0.05). The findings revealed a significant improvement in motor function following constraint-induced movement therapy, enhancing motor function and promoting stroke patients' well-being.