This research delves into the economic status of women entrepreneurs in Tirunelveli District, emphasizing their crucial role in sustainable development as human resource stewards. The study adopts a multidimensional approach, considering economic indicators, social factors, and entrepreneurial challenges to offer a comprehensive insight into the conditions influencing women-led enterprises in the area. The study combines quantitative and qualitative methods, utilizing surveys, interviews, and case studies for primary data. Secondary data from economic and demographic sources complement the research. Results reveal the varied sectors where women entrepreneurs contribute significantly to local economies and employment. The study analyzes challenges for women entrepreneurs like financial access, gender biases, and societal expectations. It also looks at how supportive policies affect their business environment. Using a critical approach, it assesses current support structures and suggests areas for improvement. The research explores how women entrepreneurs in Tirunelveli District contribute to sustainable development by promoting inclusive growth, community development, and environmental sustainability. It provides valuable insights for academia and policymakers, offering recommendations to improve economic conditions for women entrepreneurs and maximize their role as drivers of sustainable development.