A Study of Thermoacoustic Characteristics in Streptomycin Aqueous Solutions at Variable Temperatures

Rathi R.*
Department of Physics, PSN Engineering College, Tirunelveli, Tamil Nadu, India.
Periodicity:May - August'2023

Abstract

This paper investigates the thermoacoustic properties of Streptomycin sodium solutions at various concentrations and temperatures. Ultrasonic velocity measurements were employed to examine the physicochemical behavior of the antibiotic in aqueous solutions. The study focuses on understanding molecular interactions by analyzing parameters such as adiabatic compressibility (βa), intermolecular free length (Lf), acoustic impedance (Z), and relative association. The experimental data, obtained using an Ultrasonic Interferometer, was collected at frequencies of 2 MHz and temperatures ranging from 298.13 K to 308.13 K. The results reveal that ultrasonic velocity decreases with increasing concentration but increases with temperature, indicating strong solute-solvent interactions. Adiabatic compressibility increases with concentration but decreases with temperature, suggesting hydrogen bonding formation. Intermolecular free length supports the conclusion that Streptomycin acts as a structure maker. The findings contribute to the understanding of molecular interactions in Streptomycin solutions and provide valuable insights for pharmaceutical and medical applications.

Keywords

Molecular Interactions, Streptomycin Sodium, Acoustic Impedance, Adiabatic Compressibility, Intermolecular Free Length, Relative Association.

How to Cite this Article?

Rathi, R. (2023). A Study of Thermoacoustic Characteristics in Streptomycin Aqueous Solutions at Variable Temperatures. i-manager’s Journal on Physical Sciences, 2(2), 26-31.

References

[1]. Arul, G., & Palaniappan, L. (2005). Ultrasonic study of 1-butanol in pyridine with benzene. Indian Journal Pure & Applied Physics, 43, 755-758.
[2]. Aswale, S., Aswale, S. R., & Dhote, A. B. (2012). Ultrasonic studies of aspirin by relative association, Relaxation time and free volume. International Journal of Pharmacy and Pharmaceutical Sciences, 4(4), 240-243.
[4]. Bedare, G. R., Suryavanshi, B. M., & Bhandakkar, V. D. (2014). Acoustical studies on binary liquid mixture of Methylmethacr ylate in 1, 4-Dioxane at 303 K temperature. International Journals of Advanced Research in Physical Science, 1(5), 1-5.
[7]. Dash, A. K., & Paikaray, R. (2014). Acoustical study in binary liquid mixture containing dimethyl acetamide using ultrasonic and viscosity probes. Der Chem Sinica, 5(1), 81-88.
[8]. Dhote, A. B., & Bedare, G. R. (2017). Study of molecular interaction of streptomycin drug at 303 K temperature and 2 MHz. International Journal of Science, Engineering and Management, 2(3), 52-54.
[9]. Dhote, A. B., & Bedare, G. R. (2021). Acoustical Properties of Binary Mixture at 298k and at 2 MHz Frequency. International Journal of Advance Research in Science and Engineering, 8(1), 90-93.
[11]. Mistry, A. A., Bhandakkar, V. D., & Chimankar, O. P. (2013). Thermo-acoustical molecular interaction studies in ternary liquid mixtures using ultrasonic technique at 303K. Advances in Applied Science Research, 4(2), 54-59.
[12]. Mohanty, N., & Paikaray, R. (2013). Evaluation of thermodynamical acoustic parameters of binary mixture of DBP with toluene at 308K and at different frequencies. Research Journal of Chemical Sciences, 3(5), 71-82
[14]. Palani, R., Saravanan, S., & Kumar, R. (2009). Ultrasonic studies on some ternary organic liquid mixtures at 303, 308 and 313K. Rasayan Journal Chem, 2(3), 622-629.
[15]. Patil, K. C., & Dudhe, C. M. (2015). Studies on thermodynamic properties of streptomycin aqueous solutions from T= (298.15 to 308.15) K. Der Pharma Chemica, 7(9), 239-249.
[16]. Rajagopal, K., & Chenthilnath, S. (2010). Excess thermodynamic studies of binary liquid mixtures of 2-methyl-2-propanol with ketones. Indian Journal of Pure & Applied Physics, 48(50), 326–333.
[17]. Rani, R., Kumar, A., & Bamezai, R. K. (2016). Solvation behaviour of some amino acids in aqueous solutions of an antibiotic drug streptomycin sulfate at different temperatures: volumetric, acoustic and viscometric approach. Journal of Molecular Liquids, 224, 1142-1153.
[19]. Sreekanth, K., Kumar, D. S., Kondaiah, M., & Rao, D. K. (2011). Study of molecular interactions in the mixtures of secondary alcohols with equimolar mixture of ethanol+ formamide from acoustic and thermodynamic parameters. Journal of Chemical and Pharmaceutical Research, 3(4), 29-41.
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