A novel 50 V, 40 x 80 A multichannel pulse power supply, consisting of 40 numbers of 50 V, 80 A pulsed output channels for biasing pulsed RF amplifiers, is presented in this manuscript. It employs an FPGA based control and protection unit for generating drive pulses of each pulsed output channel as well as for their protection. This control unit has capability to vary the pulse width of drive pulses of pulsed output channels from 150 µs to 2 ms and frequency from 1 Hz to 50 Hz. The PSpice simulation of individual 50 V, 80 A pulsed output channel has been carried out and simulations results are also presented. Efforts have been put to minimize the inductance in the power paths of all the pulsed output channels and maintain synchronism among them. All the output channels have been simultaneously tested on dummy resistive load at 80 A peak current, 2 ms pulse width and 50 Hz switching frequency. The rise time and fall times of output pulses are observed as < 10 µs and pulse droop is observed as < 1%. The jitter between different output pulses is observed as 60 ns.