Palatal Donor Site Augmentation with Microfibrillar Collagen €” A Clinical & Histological Study

Sreeram Natarajan*, Mythili Ramachandran**, Senthil Kumar S.***, Rajasekar S.****, Krishnan V.*****, Nirmal R. M.******
Periodicity:July - September'2022

Abstract

The purpose of the present study was to clinically and histologically analyze the capacity of microfibrillar collagen to augment palatal donor soft tissue and to evaluate the augmented donor tissue clinically in root coverage procedures. The study comprised 10 patients, each with a defect of either Miller's Class I or II description, in whom the thickness of palatal donor soft tissue was deemed inadequate for a soft tissue grafting procedure. The palatal soft tissue was augmented with microfibrillar collagen, and the thickness was evaluated clinically and histologically at baseline and 2 months postoperatively. The augmented soft tissue was subsequently used for the management of gingival recession. All patients were seen periodically, and oral hygiene instructions were stressed at all appointments. Clinical parameters such as vertical recession, horizontal recession, and width of keratinized tissue were recorded at baseline, 1st month, 3rd month, and 6th month, and clinical attachment level and probing depth were recorded at baseline and 6th month. The data were analyzed using the Student paired t-test to compare pre- and post-surgery measurements. A statistically significant (P < 0.01) increase in the thickness of the soft tissue (1.244 ± 0.384 mm) was observed at two months. A statistically significant reduction in the depth of recession (3.20 ± 1.11 mm) was observed at 6 months. A statistically significant mean gain of 4.30 ± 1.34 mm was observed in the width of the keratinized tissue at 6 months. The Plaque Index remained low throughout the post-surgical period. The results of this study indicate that microfibrillar collagen has the potential to augment the palatal donor soft tissue, and the augmented tissue is stable and can be subsequently used for grafting procedures.

Keywords

Palatal Donor Site, Augmentation, Microfibrillar Collagen, Clinical Study, Histological Study.

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