Navigation surgery is applicable in any circumstance, whether a three-dimensional surgical plan from computed tomography or magnetic resonance imaging is translated into surgical reality. However, it is not always easy due to the absolute limitation of access or lack of anatomical landmarks. For successful navigation surgery, it is essential to know digital recording, intraoperative tissue position, and its changes. In maxillofacial surgery, navigational stereotaxy is highly beneficial, particularly for orbital reconstruction and hemifacial syndromes. Modern navigation systems have multiple options for referring to patient anatomy, especially for movable structures like the mandible and tongue.