Tumor in the Palate – A Case Report

L. Vijayalakshmi*, N. Jaishankar**, Ravi David Austin***, V. T. Hemalatha****
Periodicity:April - June'2018

Abstract

Pleomorphic adenomas, commonly called benign mixed tumors, are histologically composed of two subtypes of cells: epithelial and mesenchymal. Typically, these tumors are well-demarcated from the surrounding tissue by a fibrous capsule, which varies in thickness and completeness. They are one of the salivary gland tumors that affect both major and minor salivary glands, accounting for about 40-70% of cases. These lesions have been reported to contain small protrusions (pseudopodia) that extend beyond the central mass, caused by the variability in the growth rates of the various cell types. This factor contributes to recurrence rates as high as 50%, depending on the type of surgical intervention.While most pleomorphic adenomas are confined to the superficial lobe of the parotid gland, they can occasionally arise in the deep lobe of other salivary glands. Tumors arising from the minor salivary glands are uncommon clinical entities. Among them, the palate is the most commonly affected site, followed by the upper lip and buccal mucosa, respectively. Malignant degeneration, most commonly carcinoma ex pleomorphic adenoma, has been reported to occur in as many as 25% of untreated cases. In rare cases, pleomorphic adenomas degenerate into a true malignant mixed tumor and a metastasizing benign mixed tumor.

Keywords

Palatal Tumors, Neoplasms, Palatal Cancer, Tumor, Palatal Region, Malignant Tumors, Benign Tumors, Squamous Cell, Carcinoma, Adenocarcinoma, Salivary Gland Tumors.

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