Tuberculous osteomyelitis of the mandible is an extremely rare condition, particularly when compared to pyogenic infections and neoplastic diseases involving the mandible. Although rare, dentists should keep the differential diagnosis of tuberculous osteomyelitis in mind when routine therapy fails to respond. Here, we report an unusual case of primary tubercular osteomyelitis of the mandible where a biopsy of the lesion led to a near-final diagnosis of the case. The authors performed a segmental mandibulectomy distal to 36 with dearticulation of the condyle through an extraoral approach, and subsequently, antitubercular therapy subsided the swelling.