Ameloblastic Fibro-Odontoma (AFO) is a rare benign mixed odontogenic tumor with histologic characteristics of ameloblastic fibroma and complex odontoma. It has a frequency of only about 1-3% among odontogenic tumors. It is slow-growing, generally associated with a developing tooth, and occurs mostly in children and adolescents. It is a well-encapsulated tumor, and therefore local invasion and recurrence after surgery are rare. This paper presents a clinical case report of AFO in a 9-year-old boy with swelling in the posterior maxillary area that appeared radiologically as a complex odontoma but was histopathologically diagnosed as an ameloblastic fibro-odontoma.