With increasing awareness and a desire among people to preserve their dentition, there has been a considerable escalation in the number of endodontic procedures in the last decade. However, life in the fast track necessitates people to seek treatment modalities that are less time-consuming, with respect to both the number and duration of appointments. In such a scenario, the concept of single-visit endodontics is a tempting modality for practicing endodontists. This review attempts to shed light on this age-old modality and its implications in modern endodontic practice. Single-Visit Endodontic (SVE) therapy may be defined as the conservative non-surgical treatment of an endodontically involved tooth, consisting of complete chemomechanical instrumentation and obturation of the root canal system accomplished in one visit. SVE is an old concept in clinical practice and can be traced through literature for at least a hundred years. But earlier, multiple visits were considered the standard in endodontic care, and treatment in a single visit was considered radical and substandard in quality and, therefore, was not practiced.