This paper focuses on the major features of the "Peaceful End of Life Theory" and Travelbee's "Theory of the Human-toHuman Relationship." The "Peaceful End of Life Theory" has various theoretical frameworks and primarily concerns the care of terminally ill patients or individuals with incurable diseases. Travelbee's "Theory of the Human-to-Human Relationship" stated that every individual experiences suffering due to their human nature, with suffering or the disease process being the defining characteristic of one's individual state. According to Travelbee, nursing involves the relationship and communication between the nurse and the patient. In this study, the theoretical foundations, assumptions, and core principles of both theories will be analyzed, and an exploration of how they can be effectively applied in nursing practice will be conducted.