In Biotechnology industry, training is the only way to nourish the scientific and technical skills of the key employees. There are numerous ways to train the employees through theoretical and practical knowledge-based training modules for Inhouse training, On-job training, task-specific training, hands-on training, external training, refresh training, combined Inhouse and On-job training, etc. The Training Cycle is a part of training that plays a crucial role in designing, conducting, and implementing exclusive and customized training modules. It contains various steps, such as identifying deficiencies, designing inputs and outputs, and identifying the learning strategy and effectiveness of the training module, and should be evaluated through a simple grading method. Based on the available literature, trainees can improve their subject knowledge through successive training sessions. In the pandemic spreading of COVID-19, the author has an opinion on how to design and execute their training modules effectively for upgrading the scientific and technical skills of key employees in biotechnology industries like production and quality control departments. Therefore, it is suggested that they may design, conduct, and implement their developed and customized training modules for the key employees of the production and quality control departments of any biotech industry. The industries can use these training modules effectively, as described in this article. It can also be a versatile tool for developing exclusive, customized, and effective training modules.