School-Based Management (SBM) has served as a key reform program concretizing decentralization in the basic education sector in different parts of the world including the Philippines. The study used qualitative research methods including key informant interview and focus group of faculty and administrator to explore the challenges of SBM in the area of curriculum and learning in a public secondary school. Results revealed that poor foundation of basic knowledge, inadequate school facilities and instructional materials, nonobservance of time on task policy, and students’ misbehaviour and poor academic interest, low parental support, as well as errors in learner’s materials were the among the challenges being confronted by English, Science, and Mathematics (ENSCIMA) teachers that affect the successful implementation of curriculum and learning. The study recommended different strategies which include benchmarking activities through school-to-school partnerships, immersion activities, organization of quality management team, remedial and intervention sessions, additional School Learning Action Cell (SLAC) and In-Service Trainings (INSET) sessions, student orientation, parents’ summit, fora, symposium, and write-shop. These activities if collaboratively be undertaken by various stakeholders will help address the challenges that would result to efficient SBM leading to successful and quality education of the country.