Human nature is very complex and it is constantly influenced by external socio-cultural processes, which not only affect patient’s explanations about somatization but also affect person’s recovery and rehabilitation on an ongoing basis. Hence, by integrating multiple aspects of human life, health care professionals can promote personal wellbeing for their patients as a whole. Such integrated approach will enable patients, to renew their identity, and reconstruct their status in society by participating in the shared and symbolic communal ideologies. Hence, this paper is an attempt to sensitize nurses with a transcultural psychiatric perspective in order to recognize the ontological and epistemological aspect of human life and suffering. By analyzing varieties of cultural fabrications, medical explanations and underlying socio-political ethos behind the phenomenology of spirit possession in Muslim women, this paper identifies gender disparities and its socio — cultural manifestations, justifying the need of a meaning based and client centered caring discourse.