Development of smart sensor module, of high performance, large adoptability and portability, to sense the physical parameters is highly needed for electronic instrumentation. Therefore, based on an innovative technology of advanced microcontroller, an ammonia sensor module is designed and presented in this paper. The composition of nano sized (35 nm) Manganese-Zinc ferrites are synthesized by co-precipitation and formation of single phase compositions are confirmed by x-powder diffraction. The thick film sensor has been designed by screen printing technique on glass substrate and implemented for sensor module development. The electrical resistance (R) measured against concentration of ammonia gas decreases with increasing concentration of ammonia gas. On inspection of this data, it is found that, the synthesized composition is mostly sensitive to ammonia with very fast reverse recovery. Using this thick film of the compositions as ammonia sensor, data acquisition system has been designed using TLV271 operational amplifier with as high input impendence. Deploying on-chip resources of the AVR microcontroller, an embedded system is designed to produce the ammonia gas data in percentage (%). The use of on-chip ADC not only reduces the hardware complexity but also increases the accuracy due to 10-bit resolution. The software is developed in embedded C, wherein calibration of the signal to engineering unit is emphasized. This helps to enhance the portability of the present sensor module.