Formation of blood clots and plaque in blood vessels, such as in coronary artery disease (CAD), are examples of blood vessel disorders which result from the accumulation of blood components on blood vessel walls. These disorders are progressive and advance with age; however, they may go unnoticed until an unexpected death occurs. A better understanding of these diseases and the mechanisms which may be responsible will be extremely helpful in preventing their initiation and progression. The objective of this study was to examine if the effect of the Earth’s magnetic field on the electrically charged blood components could explain the accumulation of blood components and formation of plaque and blood clots on vessel walls. An in-depth understanding of such mechanism(s) could offer new methods for treatment or prevention of plaque and blood clot formation in the human vascular system.