A case study comprising of 30 instructors of higher education institutions in Eritrea, as study sample, has been carried out for investigating their readiness to integrate Technology-aided Pedagogy and Content (TPC) in teaching-learning process. Study participants were selected from Eritrea Institute of Technology (EIT) by using a blind-fold method of random sampling technique. Both qualitative and quantitative data collection methods were used. Focus group interviews were conducted in different sessions complying with ethical considerations. To collect descriptive data, semantic differential 7-point scale for bipolar adjectives was used to assess participants' attitudinal readiness and simple scale has been used to understand their level of readiness based on technology characteristics towards TPC integration in higher education. The study findings have indicated that the whole education community is well aware of the technology gadgets available around for teaching-learning support and facilitation. Almost all respondents have showed their favorable attitudinal readiness through positive value rating in a seven-point semantic differential scale of bipolar adjectives. All respondents are well aware about the technologies for teaching-learning process, and half of them have shown their level of readiness at trialability and observability of results as per the technological characteristics followed by 8 respondents at divisibility level closer to TPC integration.