In the last few years, the tall, proportioned and irregular structure exhibits more risks during earthquakes. This happens mainly due to attenuation earthquake influence and local field response which get transfer to the structure and vice versa. This can be clarified by the soil structure interaction and infill strut panel analysis. In this paper, G+3 and G+7 storey buildings with isolated foundation system are considered for analysis. The soil model assuming homogenous three diverse soil strata. The reaction of the structure in terms of SSI parameters underneath dynamic loading for well-known foundation systems & provided infill strut panel to the structure has been considered and evaluated the soil structure interaction for structures. A relative and parametric study is conceded out with the help of joint displacement, axial force, maximum bending moment, shear force, fundamental time period, etc.