The purpose of this article is to portray the effective ways of utilizing cognitive abilities for efficient e-learning. In the present scenario, globalization and advancements in technology have driven changes in the sphere of social, technological, economic environment and political landscapes at a rapid rate. E-learning is, one among the new technologies, which has become an important aspect of learning for all ages where, learning done over an electronic platform, allows the learner to learn almost anytime from anywhere. Cognitive abilities, the brain based skills allow to perform simple and complex tasks. Cognitive abilities categorized into lower order cognitive abilities include perception, attention and memory and higher order cognitive abilities include problem solving, decision making critical thinking, etc. Cognitive abilities enhance e-learning and vice-versa.