This study proposes the integration of Dorothea Orem's Self-Care Deficit Theory with Ida Jean Orlando's Nursing Process Theory to enhance the quality of patient care. Orem's theory emphasizes the importance of self-care for maintaining health and well-being, suggesting that individuals actively participate in their care to address self-care deficits. Orlando's theory focuses on the nurse-patient interaction and the nurse's role in identifying and meeting patient needs through deliberate action. Orem's theory provides a structured approach for assessing patients' self-care abilities and identifying deficits, empowering patients to participate in their care. Orlando's theory complements this by emphasizing the nurse's observational skills and their capacity to perceive and address unmet patient needs. By combining these theories, nurses can systematically assess self-care deficits, engage patients in their care, and respond to patients' immediate concerns, leading to a more holistic and patient-centered approach. By optimizing the quality of care through the integration of these two influential theories, nurses can better understand patients' self-care requirements and provide tailored interventions that not only address deficits but also enhance the overall well-being of patients. This approach holds the potential to improve patient outcomes, enhance patient satisfaction, and contribute to the advancement of nursing theory and practice. Further research and practical application of this integrated framework are warranted to fully explore its impact on the quality of patient care.