Studies on Solubility Enhancement of Telmisartan by Adsorption Method

Sharad Kamble*, Sunita Shinde**
* Department of Pharmaceutics, Nootan College of Pharmacy, Kavathe Mahankal, Sangli, Maharashtra, India.
** Department of Pharmaceutics, Tatayasaheb Kore College of Pharmacy Warnanagar, Kolhapur, Maharashtra, India.
Periodicity:October - December'2019
DOI : https://doi.org/10.26634/jchem.1.1.16370

Abstract

In this study precipitated form of Telmisartan was prepared by using Solvent evaporation technique and Spray drying technique. For this used adsorbents like Sylysia, Neusilin, and diluents like Lactose Monohydrate and Avicel. All these prepared batches were screened by performing Drug content, saturation solubility and dissolution study of the prepared batches. From this obtained optimized batch further characterized by using the dissolution test, Differential Scanning Calorimetry (DSC), X-Ray powder Diffractometer (XRD), and USP Dissolution test apparatus.

Keywords

Telmisartan, Solvent Evaporation Method, Spray Drying Technique, Adsorbent Carrier like Neusilin, Sylysia, Diluents Like Lactose Monohydrate and Avicel, Dissolution Rate.

How to Cite this Article?

Kamble, S., and Shinde, S. (2019). Studies on Solubility Enhancement of Telmisartan by Adsorption Method. i-manager's Journal on Chemical Sciences, 1(1), 17-29. https://doi.org/10.26634/jchem.1.1.16370

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