JIP_V2_N3_RP1 Venugopal Reddy Siddaiah P. Journal on Image Processing 2349-6827 2 3 1 13 Medical Image, DWT, LWT, SVD, DE, GUI, RSA, AES In this research work, a transform based medical image watermarking algorithm is used. Differential Evolution (DE) optimization technique is proposed to ensure that the watermark maintains its structural integrity along with robustness and imperceptibility. Differential Evolution (DE) optimization is employed to optimize the objective function to choose a correct type of wavelet and scaling factor. The water marking is proposed to be implemented using Discrete Wavelet Transforms (DWT), Lifted Wavelet Transform (LWT) and Singular Value Decomposition (SVD) techniques. The encryption is done using RSA and AES encryption algorithms. A Graphical User Interface (GUI) which enables the user to have ease of operation in loading the image, watermark it, encrypt it, and also retrieve the original image whenever necessary is also designed and presented in this paper. The robustness and the integrity of the watermark are tested by measuring different performance parameters and subjecting it to various attacks. July - September 2015 Copyright © 2015 i-manager publications. All rights reserved. i-manager Publications http://www.imanagerpublications.com/Article.aspx?ArticleId=3600