JDP_V3_N4_RP1 Mohamed S. El_Tokhy Ibrahim M. Fayed Mouldi A. Bedda H. Kasban Journal on Digital Signal Processing 2322–0368 3 4 1 8 Dead Time, Scintillator Detector, Decay Correction, Signal Processing Algorithms This paper discusses the signal preprocessing of the acquired radiation signal for Residence Time Distribution (RTD). Radiation signals of Molybdenum-99 (Mo99 ) were acquired through system setup. This system begins with a scintillator detector, channel counter and a Personal Computer (PC). Different forms of noise are accompanied with the RTD radiation signal. Consequently, an algorithm was proposed based on signal processing. This algorithm depends on background correction, base line restoration, statistical error computation, radioactive decay correction and dead time correction methods. Therefore, background correction was performed using two independent methods. These methods are the minimum value of the RTD radiation signal method and the subtraction method. Then, base line restoration was performed. Statistical error of the RTD radiation signal was computed. However, two different methods were studied for radioactive decay correction. Moreover, a dead time correction method is proposed. Therefore, dead time percent is obtained. Consequently, the number of lost pulses is investigated. The accuracy of the considered algorithm is determined based on statistical measurements of the acquired RTD signal. A remarkable accuracy of the dead time measurements is observed. October - December 2015 Copyright © 2015 i-manager publications. All rights reserved. i-manager Publications http://www.imanagerpublications.com/Article.aspx?ArticleId=3705