JCOM_V1_N2_RP2 Enhancing Security In Medical Image Communication With ROI Based Lossless Watermarking And Novel Digital Signature Umamageswari G.R.Suresh Journal on Computer Science 2347–6141 1 2 8 16 Reversible Watermarking, Medical Image Security, Medical Image Compression, Authenticity and Integrity, Arnold's Cat Map Method, JPEG-LS Compression, Kerberos The patient's information plays a very vital role for tele-diagnosis and tele-surgery in Medical Industry. Medical image content authentication is very important, since medical image contents are more and more widely distributed. Reversible watermarking becomes a promising technique to embed the information into medical images. This paper defines the Region of Interest (ROI) in an image and tries to embed data in Region of Non Interest (RONI). When medical image is shared through network, for the compression purpose, we propose the JPEG-LS algorithm and to provide security, to maintain secrecy, reliability and accessibility of embedded data we have proposed two Novel algorithms ACC(Advanced Classical Cipher) and SHA-I (Secure hash Algorithm) to produce the Digital Signature and used Arnold's cat map method (Arnold's Transform). Patient information, disease information and DS is embedded into DICOM images. Increase in authentication can be achieved when medical experts access secured medical images from web servers using Kerberos technique. June - August 2013 Copyright © 2013 i-manager publications. All rights reserved. i-manager Publications http://www.imanagerpublications.com/Article.aspx?ArticleId=2447